Son and successor to, ascended the throne as a mere boy (163-161 BC) under the guardianship of Lysias, who led an expedition to the relief of Jerusalem, which had been besieged by Judas Maccabeus (1 Macc 6:18-30; Ant, XII, ix, 4), who was defeated (1 Macc 6:42). Antiochus then besieged Jerusalem. Peace was finally concluded on the condition that the Jews should not be compelled to change any of their national customs (1 Macc 6:55-60; Ant, XII, ix, 7). Philip, the king’s foster-brother (2 Macc 9:29), was defeated at Antioch, but soon afterward Lysias and Antiochus were themselves defeated by Demetrius Soter, son of Seleucus Philopator (1 Macc 7:4; 2 Macc 14:2; Ant, XII, x, 1; Polyb. xxxi.19; Livy Epit. 46).